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Of concern to any user of Winstrol during a cycle should be its intoxicating effect on the liver . The drug is a 17aa structured steroid , meaning it has been structured in a way which allows it to be orally bio-available, yet this has the negative effect of making Winstrol potentially harmful to the liver. It is therefore paramount the duration of a Winstrol cycle is limited, the dose of the drug is not excessive, the user does not stack it with other hepatotoxic compounds, does not drink alcohol whilst on cycle, and does not use Winstrol if they have an underlying medical condition which effects the livers health. There are supplements available which also help protect the liver (Milk Thistle, Liv-52 etc), and these would be advisable during any Winstrol cycle .
Some side effects of prohormone supplementation can include acne breakouts, temporary hair loss, and increased sensitivity of the breast tissue. To help minimize these undesirable side effects, many users add a process known as post cycle therapy. Completing post cycle therapy entails taking an additional supplement that will offset spikes in testosterone levels and clear any toxins that have accumulated in the liver. Since prohormones are processed and broken down in the liver, it can add more stress on this organ than normal. These supplements can also lead to increases in blood pressure, which is another reason why post cycle therapy is a good idea.