Many bodybuilders combine drostanolone with other anabolic steroids . Drostanolone itself is only weakly anabolic , which is why it is not used alone during bulking cycles . jednak, when combined with other anabolic steroids , drostanolone may enhance their effects . Because drostanolone acts as an anti-estrogen through the suppression of estrogen receptors , other aromatizable steroids have less pronounced estrogen-related side effects . Also , drostanolone binds sex hormone-binding globulin ( SHBG ) which usually will bind a portion of free sex hormones and steroids , like testosterone , and inactivate them . When drostanolone binds to SHBG , the level of unbound SHBG drops , lowering the chance of it binding to other steroids , which increases their bioavailablilty .